The origin of marine invertebrate larvae has been an area of controversy in developmental evolution for over a century. Here, we address the question of whether a pelagic “larval” or benthic “adult” morphology originated first in metazoan lineages by testing the hypothesis that particular gene co-option patterns will be associated with the origin of feeding, indirect developing larval forms. Empirical evidence bearing on this hypothesis is derivable from gene expression studies of the sea urchin larval gut of two closely related (...) but differently developing congenerics, Heliocidaris tuberculata (feeding indirect-developing larva) and H. erythrogramma (nonfeeding direct developer), given two subsidiary hypotheses. (1) If larval gut gene expression in H. tuberculata was co-opted from an ancestral adult expression pattern, then the gut expression pattern will remain in adult H. erythrogramma despite its direct development. (2) Genes expressed in the larval gut of H. tuberculata will not have a coordinated expression pattern in H. erythrogramma larvae due to loss of a functional gut. Five structural genes expressed in the invaginating archenteron of H. tuberculata during gastrulation exhibit substantially different expression patterns in H. erythrogramma with only one remaining endoderm specific. Expression of these genes in the adult of H. erythrogramma and larval gut of H. tuberculata, but not in H. erythrogramma larval endoderm, supports the hypothesis that they first played roles in the formation of adult structures and were subsequently recruited into larval ontogeny during the origin and evolution of feeding planktotrophic deuterostome larvae. (shrink)

Alison Denham examines the ways in which our engagement with literary art, and metaphorical discourse in particular, informs our moral beliefs. She considers to what extent moral and metaphorical discourses are capable of truth or falsehood, warrant or justification, and how it is that we understand these discourses. This vital new study offers a fresh view of the nature of the moral and the metaphorical, and the relations between art and morality.

So far his weapons of defence are taken from a common armoury; but in the next verses he develops the argumentum ad hominem which was foreshadowed in ‘eques’ and ‘intra fortunam qui cupis esse tuam.’ Such promptings, says he, come strangely from Maecenas, whose own discreetness and self-repression will be famous in history, and whom he is resolved, so far as in him lies, to imitate.

Both the author and the date of this five-volume poem, the first Western document to link the houses of the zodiac with the course of human affairs, are uncertain. The author's name may be Marcus Manilius, or Manlius, or Mallius, and the latest datable event mentioned in the books themselves is the disastrous defeat of Varus' Roman legions by the German tribes in 9 CE. The writing shows knowledge of the work of Lucretius, but the work is not referred to (...) by any subsequent writer, suggesting that it was never widely disseminated. A manuscript was rediscovered by Poggio Bracciolini in 1416 or 1417, and editions were produced by Scaliger and Bentley, but this immensely erudite edition of 1903–1930 by the scholar and poet A. E. Housman is regarded as authoritative. Volume 4 describes the influence of the zodiacal signs on the people born under them. (shrink)

Both the author and the date of this five-volume poem, the first Western document to link the houses of the zodiac with the course of human affairs, are uncertain. The author's name may be Marcus Manilius, or Manlius, or Mallius, and the latest datable event mentioned in the books themselves is the disastrous defeat of Varus' Roman legions by the German tribes in 9 CE. The writing shows knowledge of the work of Lucretius, but the work is not referred to (...) by any subsequent writer, suggesting that it was never widely disseminated. A manuscript was rediscovered by Poggio Bracciolini in 1416 or 1417, and editions were produced by Scaliger and Bentley, but this immensely erudite edition of 1903–1930 by the scholar and poet A. E. Housman is regarded as authoritative. Volume 3 describes the working out of horoscopes. (shrink)

The 86 verses of Dorotheus printed at the end of Koechly's Manetho, 33 of which had already been published by Salmasius in his exercitationes Plinianae or his diatribae de annis climactericis, were edited by Iriarte from a scrap of manuscript at Madrid, into which they had been copied, as we now know, from the first book of the astrological treatise of Hephaestion of Thebes, who took Dorotheus for his chief authority. To these 86 verses nearly 300 more, by far the (...) most of which are preserved in the second and third books, still unpublished, of Hephaestion's work, have now been added, in the catalogus codicum astrologorum Graecorum vol. vi pp. 67 and 91–113, by Mr W. Kroll, the best editor they could have found ; a scholar who combines critical talent, knowledge of Greek, and knowledge of astrology, more happily than any of his associates, and who has emended much of the very corrupt text with conspicuous ability and success. A good many additional corrections, chiefly grammatical and metrical, have been made by Mr Ludwich in the Rheinisches Museum for 1904, pp. 42–54. (shrink)